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notch size

The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region.Notch signaling promotes proliferative signaling during neurogenesis, and its activity is inhibited by Numb to promote neural differentiation. It plays a major role in the regulation of embryonic development.

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  1. P

    trowel notch size - confused advice

    good afternoon, this website says a 12x12 square notch gives you 6mm deep adhesive. it also says a round trowel leave a 1/3 of its size, so a 10mm round lays 3mm deep. https://www.rubi.com/en/blog/how-to-choose-the-right-tile-trowel-size-step-by-step/ my tiles are 400mm x 150mm, 10mm thick...
    • penguinlicker
    • Thread
    • advice canada notch size size trowel
    • Replies: 3
    • Forum: Canada
  2. B

    Natural Stone Notch size for 15mm limestone

    So Ive been asked to price an office fitout for 200m2 of 15mm limestone Running bond format with sizes ranging from 800x500 to 300x250 - Using Laticrete Multi Max Lite What kind of trowel would be best? 15mm u-notch trowel? Just trying to gauge what the consumption will be
  3. T

    Porcelain tiles 1000mm * 200mm Notch Size

    What trowel notch size is best for laying porcelain floor tiles 1000 mm * 200 mm?
    • tilenewt
    • Thread
    • canada notch size porcelain porcelain tile porcelain tiles size tile tiles
    • Replies: 7
    • Forum: Canada
  4. S

    What size notch trowel should I use ?

    Was recommended some mapei p9 adesilex for my ceramic 360 x 275 (8mm) tiles going onto plaster in kitchen, by tile giant. It says adhesive thickness no greater than 5mm on the bag. As ive just finished doing my bathroom using tubbed adhesive and the walls were a bit off i was able to get away...
    • sb24
    • Thread
    • mapei notch size should size trowel what
    • Replies: 7
    • Forum: DIY Tiling Forum
  5. F

    15mm Square Notch

    does anyone make them ??
  6. L

    Trowel Size For Porcelain Floor Tiles

    Hi all. New to the forum. I'm doing my first tiling job in our hallway. I've got the sub floor nice and sturdy by gluing and screwing hardibacker down but need some advice on the trowel size for the job. The tiles are pretty small. They are hexagonal and roughly 26cm x 21cm rock solid 6mm...
    • Leon632
    • Thread
    • aus floor floor tiles floor tiling notch size porcelain porcelain tile size tile tiles tiling trowel trowel usa
    • Replies: 21
    • Forum: Australia
  7. T

    Adhesive To Trowel Notch Size Coverage

    Does anyone know of a formula that will calculate how much adhesive is needed for given trowel notch sizes? If a 20kg bag of cement based adhesive does about 4.5m2 (10mm trowel) then, how far would it have gone using a 3mm mosaic trowel? There's formulas for grout coverage however, I...
    • Tile seller
    • Thread
    • adhesive aus coverage notch size size tile adhesive tiling trowel trowel usa
    • Replies: 3
    • Forum: Australia
  8. D

    Trowel notch size for 305x305 travertine & calculating adhesive depth

    Good afternoon, I need to calculate the thickness of adhesive once wall tiles are laid (for corner basin mounting) Tiles are 305 x 305 trav, 10mm thick. I have these trowels from my bathroom job. the square notch is 10mm and i think the slanted notch is 12 EDIT, i also have a 6mm notched...
    • davemul
    • Thread
    • adhesive aus depth notch size size tile adhesive tiling trowel travertine trowel usa
    • Replies: 8
    • Forum: Canada
  9. J

    Trowel Notch Size??

    Hi All, I'm finally ready to tile my bathroom walls after getting all the prep done, Hardi 500 etc. The tiles I'm using are 500mm x 200mm x 8mm thick ceramic and will be fixed using a standard set bagged tile adhesive (sorry the name escapes me but was recommended on here) Can you please...
    • jond500
    • Thread
    • aus notch size size tiling trowel trowel usa
    • Replies: 3
    • Forum: Canada
  10. O

    Trowel notch size confusion !!

    I've been advised on here I need a 10mm half moon adhesive trowel to lay my 610mm x 405mm 12mm thick travertine on the plasterboard walls and marine ply floor but I'm a little confused how the size is measured is it the depth of the notch or the width of the that relates to the size. If its the...
    • ohhnoo
    • Thread
    • notch size size tiling trowel trowel usa
    • Replies: 8
    • Forum: UK Tiling Forum
  11. S

    Notch size to bed depth

    Hi guys. I was wondering if there was a way of calculating the resulting bed depth from the notch size. Take for example a 8mm square notch trowel. When applied at 45degrees this reduces the bed to around 6mm. Then when the tile is placed on to the bed and twisted in how much does this...
    • Smithy153
    • Thread
    • depth notch size size usa
    • Replies: 4
    • Forum: UK Tiling Forum
  12. S

    Trowel notch size & profile for wall tiles?

    Can anyone tell me the correct size (notch size) and shape (square, half round etc) to use for putting wall tiles up. I will be using Mapei Keraquick mixed with water. The walls are plastered brick, paint sanded off and Mapei primer applied. Tiles are 25mm x 40mm x0.8. Cheers
    • STEVEROG
    • Thread
    • notch size size tile tiles tiling trowel trowel usa wall wall tiles
    • Replies: 9
    • Forum: UK Tiling Forum
  13. S

    Help! what notch size trowel should I use?

    What is the correct size notch trowel to use to lay the following tiles..... Niro Granite Regal Vanilla porcelain. These tiles are 10 mm thick and 300mm x 300mm square. I am laying onto plywood base. The adhesive I will be using is mapei keraquick mixed with latex plus. I have a...
    • STEVEROG
    • Thread
    • help notch size should size tiling trowel trowel usa what
    • Replies: 7
    • Forum: UK Tiling Forum
  14. D

    trowel notch size

    I am looking to tile some walls. The walls are in very good condition and fairly flat. What notch size trowel is best to use. Is 5mm ok???
    • diamondtiles
    • Thread
    • notch size size tiling trowel trowel usa
    • Replies: 5
    • Forum: UK Tiling Forum
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