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pathway

In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes.: 26  In most cases of a metabolic pathway, the product of one enzyme acts as the substrate for the next. However, side products are considered waste and removed from the cell. These enzymes often require dietary minerals, vitamins, and other cofactors to function.
Different metabolic pathways function based on the position within a eukaryotic cell and the significance of the pathway in the given compartment of the cell. For instance, the, electron transport chain, and oxidative phosphorylation all take place in the mitochondrial membrane.: 73, 74 & 109  In contrast, glycolysis, pentose phosphate pathway, and fatty acid biosynthesis all occur in the cytosol of a cell.: 441–442 There are two types of metabolic pathways that are characterized by their ability to either synthesize molecules with the utilization of energy (anabolic pathway), or break down complex molecules and release energy in the process (catabolic pathway). The two pathways complement each other in that the energy released from one is used up by the other. The degradative process of a catabolic pathway provides the energy required to conduct the biosynthesis of an anabolic pathway. In addition to the two distinct metabolic pathways is the amphibolic pathway, which can be either catabolic or anabolic based on the need for or the availability of energy.Pathways are required for the maintenance of homeostasis within an organism and the flux of metabolites through a pathway is regulated depending on the needs of the cell and the availability of the substrate. The end product of a pathway may be used immediately, initiate another metabolic pathway or be stored for later use. The metabolism of a cell consists of an elaborate network of interconnected pathways that enable the synthesis and breakdown of molecules (anabolism and catabolism).

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  1. O

    how best to tile exterior reclaimed victorian tiles?

    I have pulled up and cleaned the existing tiles and have relaid the whole concrete slab to make a solid base. I have quite a bit of tiling experience being a property developer but i haven't done this type of work before. Looking at other examples on the street, the tiles are butted next to...
  2. D

    My 1st Job Restoring rediscovered Victorian tiled pathway

    Hi there, I'm restoring an old black and white tiled victorian pathway (see pictures attached). When I moved in the path was completely covered in 3 inches of concrete and terazzo tiles (horrible 1970's job). I've chipped all this away to reveal the old path, which is in reasonable condition...
  3. T

    Timeless Tiling Solutions | Victorian / Encaustic Geometric Tiling Specialist - Tyne and Wear Tiler

    Timeless Tiling Solutions | Victorian Encaustic Geometric Tiler / Tiling Specialist Timeless Tiling Solutions are based in Newcastle in the North East of England. However, we provide our services nationwide and can even travel abroad if required. We've just recently completed a Victorian...
  4. E

    Base for tiles pathway & tile/adhesive thickness

    Good morning all, I am going to be laying a new path to my front door outside, that I would like to finish with the traditional Victorian checkerboard tiles. For the base, I was planning on 100mm concrete poured over 50mm Type 1. The path will have a fall of 1:60 to match the patio. My main...
  5. Kyle Knowles

    Outdoor Tiling | Tiling outdoors

    I gave a step to tile it's 6ft x 6ft with to steps up to the main platform it's brick build then backfilled with concrete would it be acceptable to use something like kerdi membrane to cover the whole thing or even the old homelux wetroom fabric or sold I just go ditra drain or similar? ? The...
  6. M

    London Victorian Mosaic Pathway x 3

    Meticulous mosaic Tiler sought with traditional experience to lay a solid bed (little to no grout line) Victorian mosaic front of house pathway x 3 (approx. size of each pathway is c. 1.2m x 1.8m). South Greenwich. Purchased tiles are loose, not sheeted. Possible levelling screed may be...
  7. M

    Victorian Mosaic Pathway question

    Hello all, I'm in the throes of a front garden restoration project across 6 terraced houses in London, SE18 and seeking a tiler to complete 3 pathways. Some have the original Victorian pathway intact but the others have had to be removed due to their being unsalvageable. I'm getting very...
  8. C

    Victorian Pathway Problem

    So my Victorian pathway should have been completed over 5 weeks ago! The job started literally 5 weeks back but it has been stop start due to the tiler only working in dry conditions and above 5c (he has also not attended twice due to an accident on his thumb and a funeral). Anyhow the main...
  9. C

    Victorian Pathway Base?

    We are currently having our front garden landscaped. We plan to have a Victorian path laid in the spring once the weather improves. Our landscaped have liaised with our tiler and have put down a steel reinforced concrete base in readiness for when the tiler comes in spring (started/completed the...
  10. C

    Victorian Pathway Discovery

    We are having the front garden of our Victorian terrace landscaped at present. Part of the plan was to have a new black and white Victorian path laid. However on lifting the current paving we have uncovered the original victorian tiles. There path is considerably lower than the pavement so...
  11. A

    Potential pitfalls on victorian pathway

    Hi all, Ive just had a job in where the customer wants me to lay a victorian path. Its 10 x 1.3m onto concrete that was layed last October, it is flat but has a slight incline from the house to street. The main tiles are 100x100mm but the ones for the border are a quarter of the size. As this...
  12. A

    Reclaimed Victorian pathway floor tiles to lay in London

    Hi. I've bought some really nice reclaimed Victorian floor tiles to do the pathway to the front of my Victorian house (see picture). However the more I more read about it the more daunted I am by the job of laying them. The actual area to be paved it only about 1.5m2. Is there anyone in London...
  13. S

    Victorian pathway and steps Hackney - East London

    Hi, I am interested in getting a new geometric pathway installed that runs from my front gate up to my front door. The pathway itself is approx 8 foot * 4 foot with one step up to a 3 foot * 4 foot porch area. I have spent quite a lot of time looking on-line for tools to help design the...
  14. J

    Looking for tiler for Victorian mosaic pathway, west London

    Anyone out there who specializes in Victorian tiled pathways? Need one leading up to our front door and am looking for quotes. Should say am looking for a competitive quote. Thank you!! Please text me on 07785 114 971.
  15. C

    first victorian pathway

    Hi my first pathway just completed.Prob the coolest thing I have done.And it had the additional advantage of allowing me to hand my cards to passers by:drool5: I am really for the minimal spacing effect with victorian pathways!
  16. J

    Tiling external pathway on top of old concrete?

    Hi My dad has an old concrete pathway around his small bungalow and up to his front door. The old concrete is crumbling in a number of places, more so as a result of the recent freezing weather. He has had a landscaper round to look at ovr paving the concrete with paving slabs, however this...
  17. N

    Looker for tiler go reinstate Victorian pathway in NW10

    Looking for an experienced tiler to reinstate a pathway in the front garden of our terraced house in Willesden NW10. Path measures approx 3.3m x 0.9m. Would involve removing existing crazy paving. Tiles are reclaimed black and red measuring 6" square. Please let me know if you are interested...
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